Iimveliso
I-2,4-diamino-6-i-hydroxpypyritine; I-CASS.: 56-06-4
I-Synonyms: 4 (1h) -Ipyrimone, 2,6-diamino- (8I-9I); I-2,6-diamino-4-Hydroxpypyrimine; I-2,6-diamino-4-Pyrimidinol; I-44914; NSC 680818; NSC9302;
Ipropathi yamachiza ye-2,4-diamino-6-i-hydroxpypyritine
● Inkangeleko / umbala: Umhlophe uqinile
● Uxinzelelo lwe-vapor: 0.0023mmhg nge-25 ° C
● Inqaku lokunyibilika: 285-286 ° C (Diser.) (Kukhanyisiwe.)
● Isalathiso seNgxelo yeNgxelo: 1.7990 (Qikelela)
● Inqaku lokubila: I-288.5 ° C nge-760 mmhg
● I-PKA: 10.61 ± 0.50 (xela kwangaphambili)
● Inqaku leFlash: i-128.3 ° C
● I-PSA: 98.05000
● Ukuxinana: 1.84 G / CM3
● I-LOGP: 0.50900
● Indawo yokugcina i-temp :: I-4 ° C
● Kubuthathaka
● Ukuzalelwa.
Ulwazi olukhuselekileyo
● I-pictogram (s):
Xi
● Iikhowudi zengozi: xi
● Iingxelo: 36/37/38
● Iingxelo zoKhuseleko: 22-24 / 25-36-26
Iluncedo
● Inkcazo: 2,4-Damino-6-Hydroxpypyrimidine (i-Dahp) yi-Infinitive, i-Infinitor ye-GTP ye-GTP ye-GTP ye-De Novo Pernthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthesis synthes. Kwiiseli ze-huvec, i-IC50 ye-ICH4 BioSynthesis imalunga ne-0.3 mm. I-DAHP ingasetyenziselwa ukuvimba ngokufanelekileyo akukho mveliso kwiindidi ezininzi zeseli.
● Ukusetyenziswa: 2,4-Damino-6-Hydroxpyrimidine (i-DAHP) yindawo yokukhetha, i-inhibitor ye-GTP ye-GTP ye-GTP ye-De Uthando lwe-De Novo Pernthesis synthesis synthesis synthesis synthes. Kwiiseli ze-huvec, i-IC50 ye-ICH4 BioSynthesis imalunga ne-0.3 mm. I-DAHP ingasetyenziselwa ukuvimba ngokufanelekileyo akukho mveliso kwiindidi ezininzi zeseli. Iluncedo eluncedo kwi-synthesic synthesic.
I-2,4-diamino-6-i-hydroxpypyritine yicandelo lekhemikhali ngefomula yemolekyuli c4h6n4O. Ihlala isetyenziswa njengendawo ephakathi kwi-synthesis yezinto ezahlukeneyo, kubandakanya iziyobisi zamayeza kunye ne-Dyees.Iqulunqwa ye-Pyrididine ye-Pyrimidine ye-Pyrididie equka amaqela amabini e-Amino equka i-Aminon ye-Aminon. Eli sakhiwo liyenza ibhloko yokwakhiwa kwezinto eziguquguqukayo kwi-synthesis yemolekyuli entsokothileyo. Inezicelo ezininzi kumzi-mveliso wamachiza, ngakumbi kwi-synthesis yeziyobisi ze-anticiancer kunye nee-antibiotics.O-2,4-i-Diamino-6-Hydroxpyritine yindawo ebalulekileyo efumana iziko leekhemicali kunye nezixhobo ezahlukeneyo.
Intshayelelo Eneenkcukacha
I-2,4-diamino-6-i-hydroxpypyritine yicandelo lekhemikhali ngefomula yemolekyuli c4h6n4O. Yinxalenye yezinto eziphilayo ukuba ingosapho lwePyrimidine. I-compleund inomsesane we-Pyrimidine, amaqela amabini angama-Amino Isakhiwo sekhemikhali sinokubonakaliswa njenge: Ammonia | | I-H-C - C - C - N - C - C - NH2 | | oh 2,4-diamino-6-i-hydroxpyritine ineenkqubo ezahlukeneyo kumzi-mveliso wamachiza. Kubalulekile phakathi kweSiyobisi seZiyobisi ezininzi, kubandakanya neziyobisi ze-antivimor kunye ne-antitomi. Ikwasetyenziselwa ukuvelisa i-analog ye-nucleotide esetyenziswa kuPhando lweSomandleutical.
Ukongeza kwizicelo zamayeza, i-2,4-diamino-6-i-hydroxpypydyritine ikwasetyenziswa njengesithako kwi-agrochemicals. Sisithako esiphambili kwiSynthesi yoLawulo lokukhula kwezityalo kunye ne-fungicides. Kubaluleke kakhulu ukulandela iProtokholi yokhuseleko efanelekileyo xa usebenzisa i-2,4-diamino-6-i-hydroxpyritidine. Kuba ihlelwe njengezikhemikhali kakhulu, kufuneka ikhutshelwe ngononophelo kunye nezixhobo ezifanelekileyo zokukhusela kufuneka zinxitywe ukuphepha ukunxibelelana ngqo.
Kwisishwankathelo, i-2,4-diamino-6-i-hydroxpypyritine yindawo ye-organic kunye nezicelo kwiMihlaba yeZoliko kunye nezoLimo. Isakhiwo sayo sekhemikhali senza ukuba kubekho iluncedo njengeliphakathi eliphakathi kwi-synthesicals yamayeza kunye nezityalo zokukhula.
