Iimveliso
I-6-Amino-1-methyluracil
Izithethantonye:6-Amino-1-methyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione,6-amino-1-methyl-;Uracil,6-amino-1-methyl- (7CI,8CI);1-Methyl-6-aminouracil;
Ipropati yeMichiza ye-6-Amino-1-methyluracil
● Inkangeleko/uMbala: phantse imhlophe ukuya kwebeige crystalline powder kancinane
● Indawo yokunyibilika: 300 °C
● I-Refractive Index: 1.548
● PKA:9.26±0.40(Kuxelwe kwangaphambili)
● PSA:80.88000
● Ubuninzi: 1.339 g/cm3
● I-LogP: -0.76300
● Ubushushu beNdawo:Gcina kwindawo emnyama, umoya ongaphakathi, ubushushu begumbi
● Ukunyibilika.:Inyibilika kwisisombululo esixutyiweyo sesodium hydroxide.
● XLogP3:-1.3
● Ubalo lwe-Hydrogen Bond:2
● Ubalo lwe-Hydrogen Bond:3
● Ubalo lweBond eJikelekayo:0
● Ubunzima obuchanekileyo: 141.053826475
● Ukubala kweAthom Enzima:10
● Ukuntsonkotha:221
Ubunyulu/Umgangatho
I-99%, *idatha evela kubaboneleli abakrwada
I-6-Amino-1-methyluracil * idatha evela kubanikezeli be-reagent
Ulwazi oluKhuselekileyo
● IiPictogram:
● Iikhowudi zeeNgozi:Xn
● Iingxelo: 22-36/37/38
● Iingxelo zoKhuseleko:26
Iluncedo
● Uncumo lweCanonical: CN1C(=CC(=O)NC1=O)N
● Ukusetyenziswa: I-6-Amino-1-methyluracil iyaziwa ukuba yenze iziphumo zokuthintela kwi-DNA yokulungisa i-glycosylase.Ikwaziwa ukuba isetyenziswa njengento yokunqanda amadangatye.I-6-Amino-1-methyluracil ingasetyenziselwa ukulungiswa kwe-1,1?-di methyl-1H-spiro [pyrimido [4,5-b]quinoline-5,5?-pyrrolo [2,3-d] pyrimidine ]-2,2?,4,4?,6?(1?H,3H,3?H,7?H,1?H)-pentaone, ngokusabela ne isatin phambi kwe-catalytic p-toluene sulfonic acid. .
I-6-Amino-1-methyluracil, eyaziwa nangokuthi i-Adenine okanye i-6-Aminopurine, i-organic compound kunye ne-chemical formula C5H6N6O.I-purine derivative kunye necandelo le-nucleic acids.I-Adenine yenye yeenucleobases ezine ezifumaneka kwi-DNA kunye ne-RNA, kunye ne-cytosine, i-guanine, kunye ne-thymine (kwi-DNA) okanye i-uracil (kwi-RNA) .I-Adenine idlala indima ebalulekileyo kwiinkqubo zeselula ezifana nokuphindaphinda kwe-DNA kunye ne-protein synthesis.Idibanisa kunye ne-thymine (kwi-DNA) okanye i-uracil (kwi-RNA) ngokusebenzisa i-hydrogen bonding, yenza enye izibini zesiseko ezenza i-double helix isakhiwo se-DNA. iinkqubo.Isebenza njengenxalenye yee-cofactors ezifana ne-NADH, i-NADPH, kunye ne-FAD, ezibandakanyekayo kwiimpendulo ezahlukeneyo ze-enzymatic.I-Adenine iphinda isetyenziswe kwi-synthesis yeemolekyuli ezibalulekileyo njenge-ATP (i-adenosine triphosphate), eyaziwa ngokuba "yimali yamandla" yeseli.I-Adenine inokufumaneka ngeendlela ezahlukeneyo, kubandakanywa ukutsalwa kwimithombo yendalo efana namathumbu eentlanzi, okanye ngokusebenzisa i-organic. udibaniso.Ifumaneka ngokurhweba kwaye isetyenziswa ngokubanzi kuphando lwezenzululwazi, izicelo zonyango, kunye neshishini lamachiza.Xa uphatha i-adenine, iiprothokholi eziqhelekileyo zokhuseleko lwebhubhoratri kufuneka zilandelwe, kubandakanywa ukugqoka izixhobo ezifanelekileyo zokukhusela kunye nokuphatha i-compound kwindawo enomoya.Kwakhona kubalulekile ukugcina i-adenine ngokufanelekileyo ukukhusela ukuthotywa kunye nokugcina ukuzinza kwayo.
