L-Malic acid

Inkcazelo emfutshane:

Igama lemveliso:L-Malic acid

Izithethantonye:L-(-)-Malic acid, CP;Butanedioic acid, 2-hydroxy-, (2S)-;pinguosuan;Butanedioicacid,hydroxy-,(S)-;hydroxy-,(S)-Butanedioicacid;l-(ii) -malicacid;L-Gydroxybutanedioicacid;L-Mailcacid

I-CAS:97-67-6

MF:C4H6O5

MW:134.09

EINECS:202-601-5

Iindidi zeeMveliso:Izicatshulwa zezityalo;Aliphatics;MalicAcidSeries;Carboxylic Acids (Chiral);Ikhemikhali zeChiral;Chiral Reagents;Ukutya & neFind ADITIVES;Iibhloko zoKwakhiwo eziChiral;iSisombululo seZiseko;Isombululo saMacho;I-Synthetic Organic Chemistry;Izongezo zokutya kunye ne-acidulant;Imidazoles;Imidazoles;Imidazoles; bc0001

Ifayile yeMol:97-67-6.mol

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Iimpawu zeMichiza yeMalic acid

Indawo yokunyibilika	101-103 °C (isibane.)
alpha	-2 º (c=8.5, H2O)
Indawo yokubilisa	167.16°C (uqikelelo olurhabaxa)
ukuxinana	1.60
uxinzelelo lomphunga	0Pa nge25℃
isalathiso se-refractive	-6.5 ° (C=10, iAcetone)
FEMA	2655 \|L-MALIC ACID
Fp	220 °C
ixesha lokugcina.	Gcina ngaphantsi +30°C.
ukunyibilika	H₂O: 0.5 M nge-20 °C, ecacileyo, engenambala
ifomu	Umgubo
umbala	Mhlophe
Ubunzima obuthile	1.595 (20/4℃)
PH	2.2 (10g/l, H2O, 20℃)
pka	(1) 3.46, (2) 5.10(ku-25℃)
umsebenzi wamehlo	[α]20/D 30±2 °, c = 5.5% kwipyridine
Ukunyibilika kwamanzi	enyibilikayo
Merck	14,5707
Inombolo yeJECFA	619
I-BRN	1723541
InChIKey	BJEPYKJPYRNKOW-REOHCLBHSA-N
LogP	-1.68
CAS Database Reference	97-67-6(I-CAS Database Reference)
NIST Chemistry Reference	Butanedioic acid, ihydroxy-, (s)-(97-67-6)
EPA Substance Registry System	Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6)

Ulwazi ngoKhuseleko

Iikhowudi zeNgozi	Xi
Iingxelo zoMngcipheko	36/37/38
Iingxelo zoKhuseleko	26-36-37/39
WGK eJamani	3
RTECS	ON7175000
I-TSCA	Ewe
Ikhowudi ye-HS	29181980

Ukusetyenziswa kwe-asidi ye-Malic kunye ne-Synthesis

Inkcazo	Iasidi ye-L-Malic iphantse ingabinavumba (ngamanye amaxesha iphelile, ivumba le-acrid) kunye ne-tart, incasa eneasidi.Ayinampunge.Inokulungiswa ngokufakwa kwe-acid ye-maleic;ngokubiliswa kwiswekile.
Iipropati zeMichiza	Iasidi ye-L-Malic phantse ayinavumba (ngamanye amaxesha iphelile, ivumba elimuncu).Le khompawundi ine tart, acidic, nonpungent incasa.
Iipropati zeMichiza	isisombululo esicacileyo esingenambala
Isehlo	Ivela kwi-maple sap, i-apile, i-melon, i-papaya, ibhiya, iwayini yediliya, i-cocoa, i-sake, i-kiwifruit kunye ne-chicory root.
Usebenzisa	I-asidi ye-L-Malic isetyenziswa njenge-additive yokutya, i-Seletive α-amino ekhusela i-reagent ye-amino acid derivatives.I-synthon eguquguqukayo yokulungiselela i-chiral compounds kuquka i-κ-opioid receptor agonists, i-1α, i-25-dihydroxyvitamin D3 analogue, kunye ne-phoslactomycin B.
Usebenzisa	I-isomer eyenzeka ngokwemvelo yi-L-form efunyenwe kwii-apile kunye nezinye iziqhamo kunye nezityalo ezininzi.I-α-amino ekhethiweyo yokukhusela i-reagent ye-amino acid derivatives.I-synthon ehlukeneyo yokulungiswa kwee-chiral compounds ezibandakanya i-κ-opioid rece
Usebenzisa	Iphakathi kwi-chemical synthesis.I-ejenti yokutshiza kunye ne-buffering.I-agent ye-flavoring, i-flavour enhancer kunye ne-asidi ekutyeni.
Ingcaciso	I-ChEBI: Ifomu esebenzayo ye-malic acid ene-(S) -uqwalaselo.
Ukulungiselela	Iasidi ye-L-Malic inokulungiswa ngokufakwa kwe-asidi ye-maleic;ngokubiliswa kweswekile.
Inkcazo ngokubanzi	I-L-Malic acid yiasidi ephilayo efumaneka kwiwayini.Idlala indima ebalulekileyo kwi-wine microbiological uzinzo.
Izenzo zeBiochem/physiol	I-L-Malic acid yinxalenye yemetabolism yeselula.Ukusetyenziswa kwayo kuyavunywa kwii-pharmaceutics.Iluncedo kunyango lwe-hepatic ukungasebenzi kakuhle, esebenzayo ngokuchasene ne-hyper-ammonemia.Isetyenziswa njengenxalenye yokufakwa kwe-amino acid.I-L-Malic acid iphinda isebenze njenge-nanomedicine kunyango lwe-brain neurological disorders.I-TCA (umjikelezo we-Krebs) ophakathi kunye neqabane kwi-malic acid aspartate shuttle.
Iindlela zokucoca	I-Crystallize i-S-malic acid (i-charcoal) esuka kwi-ethyl acetate/pet ether (b 55-56o), igcina ubushushu obungaphantsi kwe-65o.Okanye uyinyibilikise ngokuhlaziya kwakhona kwiindawo ezilishumi elinesihlanu ze-anhydrous diethyl ether, decant, concentrate to one-third volume and crystallize it at 0o, ngokuphindaphindiweyo ukuya kwindawo yokunyibilika rhoqo.[Beilstein 3 IV 1123.]