Iimveliso
I-Methyl D-(-) -4-hydroxy-phenylglycinate
Izithethantonye:Benzeneaceticacid, α-amino-4-hydroxy-, methyl ester,(R)-;(R)-Methyl (4-hydroxyphenyl)glycinate;D-(4-Hydroxyphenyl)glycine methylester;Dp-Hydroxyphenylglycine methyl ester;Methyl; I-D-(-)-α-amino-α-(4-hydroxyphenyl) i-acetate;i-Methyl (R) -amino (4-hydroxyphenyl) i-acetate;
Ipropati yeMichiza yeMethyl D-(-)-4-hydroxy-phenylglycinate
● Uxinzelelo lomphunga: 6.03E-05mmHg kwi-25 ° C
● Refractive Index:1,57
● Indawo yokuBilisa: 335.7 °C kwi-760 mmHg
● PKA:9.74±0.26(Kuxelwe kwangaphambili)
● Indawo yokudanyaza: 156.9 °C
● PSA:72.55000
● Ubuninzi: 1.248 g/cm3
● I-LogP: 1.26530
● Ubushushu begumbi: Ubushushu begumbi
● Ukunyibilika.:DMSO (Kancinci), i-Ethanol (Kancinci, i-Sonicated), i-Methanol (Kancinci)
● XLogP3: 0.5
● Ubalo lwe-Hydrogen Bond:2
● Ubalo lwe-Hydrogen Bond yoKwamkela:4
● Inani leBond eJikelekayo:3
● Ubunzima obuchanekileyo: 181.07389321
● Ukubala kweAthom Enzima:13
● Ukuntsonkotha:176
Ubunyulu/Umgangatho
I-99% *idatha evela kubaboneleli abakrwada
I-MethylD-(-)-4-Hydroxy-phenylglycinate *idatha evela kubanikezeli be-reagent
Ulwazi oluKhuselekileyo
● IiPictogram:
● Iikhowudi zeeNgozi:
Iifayile zeMSDS
Iluncedo
● Uncumo lweCanonical: COC(=O)C(C1=CC=C(C=C1)O)N
● Ukusetyenziswa: I-Methyl D-(-)-4-Hydroxy-phenylglycinate iluncedo kwi-synthesis (+) -radicamine B. Kwakhona, isetyenziselwa ukulungiswa kwe-amoxicillin.
I-D-4-Hydroxyphenylglycine methyl ester, eyaziwa ngokuba yi-D-HPG Methyl Ester okanye i-D-4-Hydroxyphenylglycine methyl ester hydrochloride, i-chemical compound kunye ne-molecular formula C9H11NO3 kunye nobunzima be-molar ye-181.19 g / mol.Yifom ye-methyl ester ye-D-4-Hydroxyphenylglycine.D-4-Hydroxyphenylglycine methyl ester i-chiral compound enesakhiwo esikhethekileyo esibandakanya i-phenyl ring kunye ne-amino acid backbone.Yenzelwe izicelo ezahlukeneyo, kubandakanywa nokusetyenziswa kwayo njengebhloko yokwakha kwi-organic synthesis kunye ne-pharmaceutical developments.Enye isicelo esibalulekileyo se-D-4-Hydroxyphenylglycine methyl ester kukubandakanyeka kwayo kwi-synthesis yamachiza.Ingasebenza njenge-precursor kwimveliso yamachiza afana ne-β-lactam antibiotics, i-peptide analogs, kunye nezinye iikhompawundi ze-bioactive.Ukufakwa kwayo kwi-molecule yala mayeza kunokwazisa iipropati ezinenzuzo okanye ukuphucula umsebenzi wabo.Ngaphezu koko, i-D-4-Hydroxyphenylglycine methyl ester ibonisa iipropati ezinokuthi zonyango zizenzele ngokwazo.Ifundwe ngenxa ye-antioxidant, anti-inflammatory, kunye ne-neuroprotective effects.Ezi zakhiwo zenza ukuba kube ngumxholo womdla ekuphuhliseni amachiza kwiimeko ezahlukeneyo zonyango, kubandakanywa izifo ze-neurodeergenerative.Ngokufutshane, i-D-4-Hydroxyphenylglycine methyl ester i-chemical compound kunye nezicelo kwi-pharmaceutical synthesis kunye nemiphumo enokubakho yonyango.Ubume bayo obukhethekileyo kunye nendalo ye-chiral iyenza ixabiseke njengebhloko yokwakha kuphuhliso lwechiza, kwaye imisebenzi yalo yebhayoloji ebonakalisiweyo icebisa amandla ayo kwizicelo ezahlukeneyo zonyango.
