Iimveliso
I-Pyrimidine-2,4 (1h, 3h) -e
Izithethantonye: U-Ucinera
Impahla yemichiza yePyrimidine-2,4 (1h, 3h) -e
● Inkangeleko / umbala: ipowder emhlophe
● Uxinzelelo lwe-vapor: 2.27e-08mmhg nge-25 ° C
● Inqaku lokunyibilika:> I-300 ° C (ikhanyisiwe.)
● Isalathiso seNgxelo yeNgxelo: 1.501
● Inqaku lokubila: I-440.5 ° C nge-760 mmhg
● I-PKA: 9.45 (nge-25 ℃)
● Inqaku leFlash: 220.2OC
● psa:I-65.72000
● Ukuxinana: 1.322 g / cm3
● I-LGPP: -0.93680
● Indawo yokugcina i-temp.15C ukuya + 30c
● Ukuzithoba.
● Ukuzola amanzi
● I-XlogP3: -1.1
● I-Hydrogen Bop Count Count: 2
● Ubalo lwe-Hydrogen Bopptor: 2
● Ibhondi enzobiziweyo: 0
● Ubunzima obuthe ngqo: 112.027277375
● I-Atom Comtop Com: 8
● Ukuntsonkotha: 161
Ulwazi olukhuselekileyo
● I-pictogram (s):
Xi
● Iikhowudi zengozi: xi
● Iingxelo zoKhuseleko: 22-24 / 25
Iluncedo
Iiklasi zekhemikhali:Iiarhente zebhayoloji -> i-nucleic acids kunye nezixhobo
I-Canonical iyancuma:C1 = cnc (= o) NC1 = o
Iiklinikhi zakutshanje zamvanje:Ukufundwa kwe-0.1% ye-UCRAL Cream Cream (I-UTC) yokuthintela i-syndrome yenyawo
Izilingo zekliniki zamva nje ze-EU:I-Onderzoek Naar De Famemacokiinetiek van Urac Barale Toedie Todie Tij Pai?
Uvavanyo lweklinikhi lwakutshanje
IISEBE:Uphando lwebhayoloji, iziyobisi syntheis; Ukusetyenziswa njengamachiza aphakathi, kwakwasetyenziswa kwi-orntaic synthesic synthesic nitrogenous kwisiseko se-gon thcleosides. I-antineplastic kuphando lwe-biochemical. I-UCRAL (i-lamivudine ep of if
Inkcazelo:I-UCYIL sisiseko se-Pyrimidine kunye necandelo elisisiseko le-RNA apho libophelela khona kwi-Adenine ngeBond ye-hydrogen. Iguqulwe ibe yi-nucleoline ye-nucleoline ngokongezwa kwe-ribose molose, emva koko uye kwi-nuclootide curidine monophosphate ngokungezwa kweqela le-phosphate.
Intshayelelo Eneenkcukacha
I-Uracil yindawo ye-organic yeyosapho ye-Pyrimidine Derivatives. Yimolekyuli ye-heterocyclic ye-rolemacc equka i-Pyrimidine iringi ene-atoni ezimbini ezingabamelwane. U-Urackil unefomula yekhemikhali c4h4N2O2 kunye nobunzima bemolekyuli ye-112.09 g / mol.
I-Urackil yenye yee-nucleobases ezine ezifumaneka kwizinto zemvelo zeRNA (i-ribonucleic acid). Idlala indima ebalulekileyo kwiprotein synthesis kunye nentetho yesifo. Kwi-RNA, izibini ze-cudeil nge-adenine nge-hydrogen ye-hydrogen, kwaye le ntaka inyanzelekile inceda ekusebenziseni ulwazi lwemfuzo.
I-Urachil inokufumaneka kwezinye iimolekyuli ezibalulekileyo zebhayoloji. Umzekelo, yinto ebalulekileyo yemolekyuli ene-molecule ebizwa ngokuba yi-ATP (Adenosine Trichosphate). I-Urackil Derivastitives, ezinjenge-5-fluorouracil, isetyenziswe njengeearhente ze-antices ngenxa yokuphazamisa ukuphindaphinda i-DNA kunye neCandelo.
Ukongeza ekuba ngathi ukubaluleka kwayo, i-UCRAL ineemichiza ezahlukeneyo kunye nemizi mveliso. Isetyenziswa njengesixhobo sokuqala se-synthesis ye-surmaceuticals, i-agrochemicals, kunye ne-dyas. I-Uraclil Drivativetives ikwasebenza kwimveliso ye-herbicides kunye ne-fungicides. Ngaphaya koko, i-urackil inokusetyenziswa njengomphawu omakishi kuhlalutyo kwaye njengesixhobo kwimolekyuli yophando lwe-molekri.
I-UCRAL yi-crystalline emhlophe eqinile inyibilikiswe ngamanzi. Inokuzinza phantsi kweemeko eziqhelekileyo kodwa inokuthi iphendule kwakhona, njengokuphendula kwe-oxition kunye nokuthatha izinto, phantsi kweemeko ezithile. I-complet inendawo yokunyibilika ye-335-338°C kunye nendawo yokubila ye-351-357°C.
Ngokubanzi, i-urackil licandelo elibalulekileyo kwiinkqubo zebhayoloji ze-RNA kwaye zinezicelo ezibalulekileyo kuwo amashishini okwenziwa kwebhayiliza kunye nemichiza.
Isicelo
I-UCRAL ineendlela ezahlukeneyo kwimimandla eyahlukeneyo, kubandakanya:
Ishishini lamachiza:U-Uracil kunye nee-dervatives zayo zisetyenziselwe ukuphucula amachiza ngeenjongo ezahlukeneyo. Umzekelo, i-5-Floorouracil sisichithwa esisetyenziswa nge-chemotheratherapy sisebenzisa iintlobo ezithile zomhlaza. Amachiza ase-I-Anticlil-esekwe kwi-antivilral, afana ne-idorgridine kunye ne-trifridine, isetyenziselwa ukuphatha usulelo lweliso lwe-nyral.
Ezolimo:I-UCRAL Drivatives isetyenziswa kwimveliso ye-herbicides kunye ne-fungicides. Ezi ngqokelela zinceda ukulawula ukukhula kokhula nokukhusela izityalo ezivela kusulelo lwefungi.
I-Chemistry yohlalutyo:I-UCRAL ihlala isetyenziswa njengommakisi we-chromatographic okanye umgangatho wangaphakathi kwiindlela zohlalutyo. Ingasetyenziswa njengengxelo yesalathiso yokuchonga ixesha lokugcina kunye nokulinganisa ezinye iikhomputha kwisampulu.
UPhando lwe-Molekortur biology:I-Urackil isetyenziswa kwiindlela ezahlukeneyo zebhayiloji zemolekyuli, ezinjenge-Polymerase Chain impendulo (i-PCR), ukulandelelana kwe-DCR), kunye ne-STE-Reddsis. Isebenza njenge template ye-DNA Synthesis okanye njengecandelo lokudala utshintsho oluthile ku-DNA ukulandelelana.
Ishishini lokutya:U-UracIl ngamanye amaxesha usetyenziswa njengokuphucula incasa kwishishini lokutya, ngakumbi ekuvelisweni kokutya okuphezulu kunye neziselo.
I-cosmetics:I-Uraclil Derivatives isetyenziswa kwiimveliso ze-cosmetic zepropathi yazo yokunyibilikisa kunye nolusu. Banokunceda ukuphucula i-hydration yolusu kwaye bakhusele ngokuchasene noxinzelelo lwendalo.
Uphando nophuhliso:U-Uracil ukwaqeshwa kwi-biochemical kunye nophando oluphambili njengendawo yokuqalisa okanye i-regether ephakathi yokuqesha ezinye izinto ezenziwa ngumsebenzi webhayoloji okanye ukufundisisa i-qualolism.
Uluhlu olubanzi lwe-UCRAL lubonisa ukubaluleka kwayo kumayeza anje ngamayeza, ezolimo, i-chemistry, kunye ne-bietechnology. Abaphandi bayaqhubeka nokuphonononga iindlela ezintsha zokusebenzisa iipropathi zayo ukuze ziqhubekeke ezinye kwezi ndawo.
