Iimveliso
Uracil Pyrimidine-2,4 (1H,3H) -dione
Izithethantonye:Uracil
Ipropati yeMichiza ye-Uracil
● Imbonakalo/Umbala:umgubo omhlophe
● Uxinzelelo lomphunga: 2.27E-08mmHg kwi-25 ° C
● Indawo ekunyibilika kuyo:>300 °C(lit.)
● I-Refractive Index: 1.501
● Indawo yokuBilisa: 440.5 ° C kwi-760 mmHg
● PKA:9.45(ku-25℃)
● Indawo edanyazayo:220.2oC
● PSA: 65.72000
● Ubuninzi: 1.322 g/cm3
● I-LogP:-0.93680
● Ukugcinwa Kwexesha: + 15C ukuya +30C
● Ukunyibilika.: I-Acid Acid (Kancinci), i-DMSO (Kancinci, ishushu, i-Sonicated), i-Methanol (Kancinci,
● Ukunyibilika kwamanzi
● XLogP3:-1.1
● Ubalo lwe-Hydrogen Bond:2
● Ubalo lwe-Hydrogen Bond:2
● Ubalo lweBond eJikelekayo:0
● Ubunzima obuchanekileyo: 112.027277375
● Ukubala kweAtom eNzima:8
● Ukuntsonkotha:161
Ubunyulu/Umgangatho
I-99%, *idatha evela kubaboneleli abakrwada
Uracil *idatha evela kubaboneleli be-reagent
Ulwazi oluKhuselekileyo
● IiPictogram:
Xi
● Iikhowudi zeeNgozi:Xi
● Iingxelo zoKhuseleko: 22-24/25
Iluncedo
● Iiklasi zeMichiza: Ii-Biological Agents -> I-Nucleic Acids kunye nezinto eziphuma kuyo
● Uncumo lweCanonical: C1=CNC(=O)NC1=O
● Iimvavanyo zeklinikhi zakutsha nje: Uphononongo lwe-0.1% ye-Uracil Topical Cream (UTC) yoThintelo lwe-Hand-Foot Syndrome
● Uvavanyo lwezonyango lwakutshanje lwe-EU: Onderzoek naar de farmacokinetiek van uracil na orale toediening bij pati?nten met colorectaal carcinoom.
● Uvavanyo lweKlinikhi lwakutshanje lwe-NIPH: Uvavanyo lwesigaba se-II se-uracil ointment yokuthintela i-capecitabine eyenziwa yi-hand-foot syndrome (HFS):.
● Ukusetyenziswa: Kuphando lwe-biochemical, i-drug synthesis;isetyenziswa njengeziphakathi zoxubo, ikwasetyenziswa kwi-organic synthesis Isiseko se-nitrogenous kwi-nucleosides ye-RNA.i-antineoplastic Kuphando lwe-biochemical.I-Uracil (i-Lamivudine EP Ukungcola F) sisiseko senitrogen kwi-nucleosides ye-RNA.
● Inkcazo: I-Uracil iyisiseko se-pyrimidine kunye nenxalenye esisiseko ye-RNA apho ibophelela kwi-adenine nge-hydrogen bonds.Iguqulwa ibe yi-nucleoside uridine ngokudityaniswa kwe-ribose moiety, emva koko kwi-nucleotide uridine monophosphate ngokongezwa kweqela le-phosphate.
